'The Centre for Ecology and Evolution (CEE), the Centre for Integrative Systems Biology at Imperial College (CISBIC), and the Natural History Museum, are organising a one day symposium on *Systems Biology and Evolution* on Wednesday 18th October 2006, in the Flett lecture theatre, the Natural History Museum, London.

Speakers include Buzz Baum (Ludwig Institute for Cancer Research, UCL),
Michael Akam (Cambridge), David Robertson (Manchester), David Fell (Oxford Brookes University), M. Madan Babu (LMB, Cambridge), Yitzhak Pilpel (Weizmann Institute, Israel), Joachim Hermisson (Munich) and Cyrus Chothia (LMB Cambridge).

For full details, please go to

http://www.ucl.ac.uk/~ucbtcee/cee/events.html
<http://www.ucl.ac.uk/%7Eucbtcee/cee/events.html>

The meeting is free, but lecture theatre space is limited. To ensure a place, please register at bioinformatics@imperial.ac.uk

For other enquries, please contact Dr Michael Stumpf (organiser) on m.stumpf@ic.ac.uk.

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Programme:

9:00 Welcome and Introduction
9:10 The Evolution of homeostasis and stem cell-like behavioiur in multi-cellular organisms
Dr. Buzz Baum, Ludwig Cancer Institute, UCL
9:50 The evolving gene network underlying arthropod segmentation: Can we get at the systems biology?
Prof. Michael Akam, University Museum of Zoology, Cambridge University

10:30 Tea & Coffee

11:00 Visualization and Reconstruction of PPI Network Evolution
Dr. David Robertson, Bioinformatics, University of Manchester
11:40 Does the current structure of the metabolic network reveal anything

about its early evolution?
Prof. David Fell, Oxford Brooks University

12:20 Lunch Break

14:00 Structure and Evolution of transcriptional regulatory networks
Dr. M. Madan Babu, LMB, Cambridge
14:40 Regulation of translation efficiency and phenotypic divergence of yeast species.
Dr. Yitzhak Pilpel, Weizmann Institute, Rehovot, Israel.

15:20 Tea and Coffee

15:50 Canalization and hidden genetic variation
Dr. Joachim Hermisson, Evolutionary Biology, University of Munich
16:30 Protein domain architecture and Biological Complexity
Dr. Cyrus Chothia, LMB Cambridge

17:10 Discussion session

17:40 =AD 18:40 Drinks reception, Imperial college